BDBM50346164 5-(4-methoxy-2-(oxiran-2-ylmethoxy)phenyl)-3-phenylisoxazole::CHEMBL1783787

SMILES COc1ccc(-c2cc(no2)-c2ccccc2)c(OCC2CO2)c1

InChI Key InChIKey=QKWRKAAALNNZSC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346164   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50346164(5-(4-methoxy-2-(oxiran-2-ylmethoxy)phenyl)-3-pheny...)
Affinity DataIC50:  3.11E+4nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50346164(5-(4-methoxy-2-(oxiran-2-ylmethoxy)phenyl)-3-pheny...)
Affinity DataIC50:  3.13E+4nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed