BDBM50346172 2-(pyridin-3-ylmethyl)quinuclidine bis(2,2,2-trifluoroacetate)::CHEMBL1783881::CHEMBL1789658

SMILES C(C1CC2CCN1CC2)c1cccnc1

InChI Key InChIKey=XOXNEDDHVCBSGK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50346172   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50346172(2-(pyridin-3-ylmethyl)quinuclidine bis(2,2,2-trifl...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]nicotine human alpha4beta2 nAChR in SH-EP1 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Targacept

Curated by ChEMBL
LigandPNGBDBM50346172(2-(pyridin-3-ylmethyl)quinuclidine bis(2,2,2-trifl...)
Affinity DataKi:  449nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50346172(2-(pyridin-3-ylmethyl)quinuclidine bis(2,2,2-trifl...)
Affinity DataKi:  979nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed