BDBM50346266 (2R,3R,4S,5S,6R)-2-(4-chloro-3-(4-cyclopropylbenzyl)-1H-indol-1-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol::CHEMBL1782370

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)n1cc(Cc2ccc(cc2)C2CC2)c2c(Cl)cccc12

InChI Key InChIKey=XPBIIANBNARGIV-PFKOEMKTSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50346266   

TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50346266((2R,3R,4S,5S,6R)-2-(4-chloro-3-(4-cyclopropylbenzy...)
Affinity DataEC50:  14nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50346266((2R,3R,4S,5S,6R)-2-(4-chloro-3-(4-cyclopropylbenzy...)
Affinity DataEC50:  2.30nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]-alpha-methylglucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50346266((2R,3R,4S,5S,6R)-2-(4-chloro-3-(4-cyclopropylbenzy...)
Affinity DataEC50:  27nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed