BDBM50347447 CHEMBL1802096
SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)CP([O-])(=O)OP([O-])(=O)CP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O
InChI Key InChIKey=HHAKBDBCUAPUJT-LAMCKDNKSA-J
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50347447
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataKi: 1.47E+5nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as enzyme-substrate-inhibitor dissociation constant using pnp-TMP as the substrate after 15...More data for this Ligand-Target Pair
Affinity DataEC50: 9.00E+3nMAssay Description:Agonist activity at GFP tagged-human P2Y1 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluorescen...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University
Curated by ChEMBL
Bar-Ilan University
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair