BDBM50350107 CHEMBL1230692
SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@@](O)(=O)O[P@](O)(=O)OC[C@H]2NC[C@H](O)[C@@H]2O)[C@@H](O)[C@H]1O
InChI Key InChIKey=NDQDTBCXPOIQGT-UHNJQBFTSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50350107
TargetPoly(ADP-ribose) glycohydrolase(Rattus norvegicus)
Kumamoto Health Science University
Curated by ChEMBL
Kumamoto Health Science University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassayMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of PARG using [alpha-32P]ADP-ribose polymers after 5 mins by TRAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:The compound was tested for its ability to inhibit recombinant bovine polyadenosine diphosphoribose glycohydrolase catalytic fragment (rPARG-CF)More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:The compound was tested for its ability to inhibit bovine thymus polyadenosine diphosphoribose glycohydrolase (bPARG)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:The compound was tested for its ability to inhibit recombinant bovine polyadenosine diphosphoribose glycohydrolase catalytic fragment (rPARG-CF)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of PARP-1 using [32P]-NAD+ after 15 minsMore data for this Ligand-Target Pair