BDBM50350467 BL-S578::CEFADROXIL::Cefadrops
SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccc(O)cc1)C2=O)C(O)=O
InChI Key InChIKey=BOEGTKLJZSQCCD-UEKVPHQBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 23 hits for monomerid = 50350467
TargetSolute carrier family 15 member 2(Homo sapiens (Human))
Medical College Of Georgia
Curated by ChEMBL
Medical College Of Georgia
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:TP_TRANSPORTER: inhibition of Chephalexin uptake in SKPT cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 15 member 2(Homo sapiens (Human))
Medical College Of Georgia
Curated by ChEMBL
Medical College Of Georgia
Curated by ChEMBL
Affinity DataKi: 2.80E+3nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake in SKPT cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 15 member 2(Rattus norvegicus)
Biozentrum Of The Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Biozentrum Of The Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in SKPT cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 15 member 2(Rattus norvegicus)
Biozentrum Of The Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Biozentrum Of The Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 15 member 2(Homo sapiens (Human))
Medical College Of Georgia
Curated by ChEMBL
Medical College Of Georgia
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Binding affinity to human PepT2 in SKTP cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.14E+3nMAssay Description:TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.62E+3nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.62E+3nMAssay Description:Inhibition of human OAT3 using estrone-3-sulfate as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.45E+6nMAssay Description:TP_TRANSPORTER: inhibition of Cefixim uptake in Caco-2 cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 15 member 1(Rattus norvegicus)
Kyoto University Hospital
Curated by ChEMBL
Kyoto University Hospital
Curated by ChEMBL
Affinity DataKi: 2.17E+6nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT1-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.20E+6nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in Caco-2 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.20E+6nMAssay Description:Binding affinity against membrane transport protein PEPT1 in human Caco-2 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.10E+6nMAssay Description:TP_TRANSPORTER: inhibition of VACV uptake in PEPT1-expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+6nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 15 member 2(Homo sapiens (Human))
Medical College Of Georgia
Curated by ChEMBL
Medical College Of Georgia
Curated by ChEMBL
Affinity DataIC50: 6.60E+4nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 50 uM) in PEPT2-expressing HeLa cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+5nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 25 uM) in PEPT1-expressing HeLa cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.78E+6nMAssay Description:Inhibition of rat OAT3 using estrone-3-sulfate as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.78E+6nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 6(Rattus norvegicus)
Kyorin University School Of Medicine
Curated by ChEMBL
Kyorin University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: >2.00E+6nMAssay Description:TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair