BDBM50352517 CHEMBL1614782

SMILES Cc1cc(N)nc(C[C@@H]2CNC[C@@H]2OCCNCC(F)(F)c2cccc(F)c2)c1

InChI Key InChIKey=IRAITVAESBBILD-BEFAXECRSA-N

Data  3 KI

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50352517   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50352517(CHEMBL1614782)
Affinity DataKi:  110nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli assessed as reduction in formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50352517(CHEMBL1614782)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of mouse iNOS expressed in Escherichia coli assessed as reduction in formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50352517(CHEMBL1614782)
Affinity DataKi:  1.30E+5nMAssay Description:Inhibition of bovine eNOS expressed in Escherichia coli assessed as reduction in formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair