BDBM50352572 CHEMBL1825157::US8772288, 51

SMILES Cc1ccc(cc1-c1cc2NC(=O)C3(CCCC3)c2cn1)C(=O)NC1CC1

InChI Key InChIKey=GQMZOGFWLDFTKS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50352572   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM50352572(CHEMBL1825157 | US8772288, 51)
Affinity DataIC50:  0.800nMpH: 7.5 T: 2°CAssay Description:Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM50352572(CHEMBL1825157 | US8772288, 51)
Affinity DataIC50:  64nMAssay Description:Inhibition of p38alpha in human whole blood assessed as reduction in TNF-alpha production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM50352572(CHEMBL1825157 | US8772288, 51)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed