BDBM50352735 CHEMBL1823062::US8835436, Example 92

SMILES CC(C)Cn1c(C)nc(C(=O)NCCCN2CCN(CC2)c2cccc(C)c2C)c1C

InChI Key InChIKey=VLJJUAAYWAAFPF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50352735   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM50352735(CHEMBL1823062 | US8835436, Example 92)
Affinity DataIC50:  217nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM50352735(CHEMBL1823062 | US8835436, Example 92)
Affinity DataIC50:  1.01E+4nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352735(CHEMBL1823062 | US8835436, Example 92)
Affinity DataIC50:  436nMAssay Description:Displacement of [3H]impiramine from human serotonin transporter membrane expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM50352735(CHEMBL1823062 | US8835436, Example 92)
Affinity DataIC50:  217nMAssay Description:Displacement of [3H]ketanserin from human recombinant serotonin 5-HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM50352735(CHEMBL1823062 | US8835436, Example 92)
Affinity DataIC50:  1.01E+4nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352735(CHEMBL1823062 | US8835436, Example 92)
Affinity DataIC50:  436nMpH: 7.4Assay Description:For serotonin transporter binding assays, a reaction mixture with a final volume of 0.25 ml was prepared by mixing a test compound, human serotonin t...More data for this Ligand-Target Pair
In DepthDetails US Patent