BDBM50353000 CHEMBL1825187

SMILES Cc1ccc(F)cc1Oc1c(C(=O)N2CCNCC2)c2ccnc(Cc3ccccc3)c2n1-c1ccccc1

InChI Key InChIKey=UIBPLELQTBSRIZ-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50353000   

TargetRenin(Homo sapiens (Human))
Deutschland

Curated by ChEMBL
LigandPNGBDBM50353000(CHEMBL1825187)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant renin using dabcyl-gamma-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS as substrate preincubated for 30 mins afte...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Deutschland

Curated by ChEMBL
LigandPNGBDBM50353000(CHEMBL1825187)
Affinity DataIC50:  192nMAssay Description:Inhibition of human recombinant renin using dabcyl-gamma-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS as substrate preincubated for 30 mins afte...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Deutschland

Curated by ChEMBL
LigandPNGBDBM50353000(CHEMBL1825187)
Affinity DataIC50:  226nMAssay Description:Inhibition of human recombinant renin using dabcyl-gamma-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS as substrate preincubated for 30 mins afte...More data for this Ligand-Target Pair