BDBM50353292 CHEMBL1830698

SMILES C1Cc2sc(Nc3ccccn3)nc2-c2cn[nH]c12

InChI Key InChIKey=MIOXQGMSPSEKCA-UHFFFAOYSA-N

Data  6 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50353292   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353292(CHEMBL1830698)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu5 receptor assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353292(CHEMBL1830698)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu2 receptor assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353292(CHEMBL1830698)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353292(CHEMBL1830698)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu1 receptor assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353292(CHEMBL1830698)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353292(CHEMBL1830698)
Affinity DataEC50:  220nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353292(CHEMBL1830698)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu7 receptor assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353292(CHEMBL1830698)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353292(CHEMBL1830698)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353292(CHEMBL1830698)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353292(CHEMBL1830698)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353292(CHEMBL1830698)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu3 receptor assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed