BDBM50353846 CHEMBL1831156::US9604926, Compound CM-338::US9724435, Compound CM-338

SMILES Fc1ccc(cc1)N1CCN(CCCCn2ccc3ccccc23)CC1

InChI Key InChIKey=KRXYVKJBVSRNHI-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50353846   

TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
The University Of Mississippi

US Patent
LigandPNGBDBM50353846(CHEMBL1831156 | US9604926, Compound CM-338 | US972...)
Affinity DataKi:  1.09nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50353846(CHEMBL1831156 | US9604926, Compound CM-338 | US972...)
Affinity DataKi:  1.09nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50353846(CHEMBL1831156 | US9604926, Compound CM-338 | US972...)
Affinity DataKi:  71.5nMAssay Description:Displacement of (-)-[3H]pentazocine from sigma 1 receptor in rat brain membrane after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50353846(CHEMBL1831156 | US9604926, Compound CM-338 | US972...)
Affinity DataKi:  170nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50353846(CHEMBL1831156 | US9604926, Compound CM-338 | US972...)
Affinity DataKi:  170nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent