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BDBM50354009 CHEMBL1828894

SMILES: CCCN(CCC)c1c(C2CCCC2)c(Nc2ccc(OC)cc2Cl)nc2ccnn12

InChI Key: InChIKey=JBEUTXLYRIKNHE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354009   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50354009
PNG
(CHEMBL1828894)
Show SMILES CCCN(CCC)c1c(C2CCCC2)c(Nc2ccc(OC)cc2Cl)nc2ccnn12
Show InChI InChI=1S/C24H32ClN5O/c1-4-14-29(15-5-2)24-22(17-8-6-7-9-17)23(28-21-12-13-26-30(21)24)27-20-11-10-18(31-3)16-19(20)25/h10-13,16-17H,4-9,14-15H2,1-3H3,(H,27,28)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 308n/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counting


Bioorg Med Chem 19: 5955-66 (2011)


Article DOI: 10.1016/j.bmc.2011.08.055
BindingDB Entry DOI: 10.7270/Q24X5862
More data for this
Ligand-Target Pair