BDBM50354012 CHEMBL1828897

SMILES CCCN(CCC)c1cc(nc2ccnn12)N(CC)c1ccc(OC)cc1Cl

InChI Key InChIKey=MLIOXGQBPYIGQL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50354012   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50354012(CHEMBL1828897)
Affinity DataEC50:  18.6nMAssay Description:Antagonist activity at human CRF1 receptor expressed in CHO-K1 cells assessed as inhibition of CRF-induced cAMP accumulation after 15 mins by cAMP en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50354012(CHEMBL1828897)
Affinity DataIC50:  31.6nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed