BDBM50354028 CHEMBL1830524
SMILES CCC(CC)n1ccc2c(Nc3ccc(OC)cc3CC)nc3ccnn3c12
InChI Key InChIKey=JWJSWPQPNAEHNQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50354028
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataEC50: 3.5nMAssay Description:Antagonist activity at human CRF1 receptor expressed in CHO-K1 cells assessed as inhibition of CRF-induced cAMP accumulation after 15 mins by cAMP en...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma countingMore data for this Ligand-Target Pair