BDBM50354357 CHEMBL1836471::DT2000-0142665, MAP03

SMILES Nc1ncnc2sc3CCCCc3c12

InChI Key InChIKey=QXPQVUQBEBHHQP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50354357   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50354357(CHEMBL1836471 | DT2000-0142665, MAP03)
Affinity DataIC50:  2.25E+3nMAssay Description:Z'Lyte AssayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50354357(CHEMBL1836471 | DT2000-0142665, MAP03)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human recombinant renin expressed in FreeStyle 293 expression system using FITC-epsilonAcp-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL
LigandPNGBDBM50354357(CHEMBL1836471 | DT2000-0142665, MAP03)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of LIMK1 using cofilin-2 as substrate after 60 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research

Curated by ChEMBL
LigandPNGBDBM50354357(CHEMBL1836471 | DT2000-0142665, MAP03)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of LIMK1 using cofilin-2 as substrate after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed