BDBM50354414 CHEMBL1836842

SMILES CC1(C)CNCCN1C(=O)c1ccc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)C2CC2)cc1Cl

InChI Key InChIKey=MEQKJTZVPMNRIL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50354414   

TargetAurora kinase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354414(CHEMBL1836842)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of AurBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354414(CHEMBL1836842)
Affinity DataIC50:  180nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354414(CHEMBL1836842)
Affinity DataIC50:  2nMAssay Description:Inhibition of BRK pretreated for 30 mins by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354414(CHEMBL1836842)
Affinity DataIC50:  5nMAssay Description:Inhibition of phosphorylated SAM68 in 293 WT-PTK6 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed