BDBM50355094 CHEMBL1835317

SMILES CC(C)[C@H](NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CC[C@H](CC(C)(C)C)[C@H]1C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=NUKXBEZPHGEALY-OEIUQNLFSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50355094   

TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355094(CHEMBL1835317)
Affinity DataIC50:  2.36E+3nMAssay Description:Inhibition of human Myc-DDK tagged caspase-2 expressed in HEK293 T17 cells using Ac-VDVAD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355094(CHEMBL1835317)
Affinity DataIC50:  50nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355094(CHEMBL1835317)
Affinity DataIC50:  2.93E+3nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355094(CHEMBL1835317)
Affinity DataIC50:  7.84E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged human caspase-3 expressed in HEK293 T17 cells using Ac-DEVD-AMC coumarin-120 as substrate pre-incubated for 2 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed