BDBM50355116 CHEMBL493923::US10278929, Compound 22::US11337935, Compound 22
SMILES Oc1ccccc1C1NC(=O)C(C#N)=C(SCc2ccccc2)S1
InChI Key InChIKey=CBPDTXHHGBVEIJ-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50355116
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
Affinity DataIC50: 4.79E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
Target4-diphosphocytidyl-2-C-methyl-D-erythritol kinase(Yersinia pestis)
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of His6-tagged Yersinia pestis KIM6 CDP-ME kinase assessed as ADP production after 30 mins by Kinase Glo luminescence-based assay or stand...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
Affinity DataIC50: 4.79E+3nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
The Board Of Trustees Of The Leland Stanford Junior University
US Patent
Affinity DataIC50: 4.79E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human galactokinase after 30 mins by Kinase-GloTM assayMore data for this Ligand-Target Pair