BDBM50355310 CHEMBL1835113

SMILES CN1CCC(=CC1)c1c[nH]c2cc(ccc12)N=C(N)c1cccs1

InChI Key InChIKey=ZDQVFEQUDNDGSS-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50355310   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355310(CHEMBL1835113)
Affinity DataIC50:  800nMAssay Description:Inhibition of human nNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355310(CHEMBL1835113)
Affinity DataIC50:  2.65E+4nMAssay Description:Inhibition of human eNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355310(CHEMBL1835113)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of human iNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355310(CHEMBL1835113)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant nNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355310(CHEMBL1835113)
Affinity DataIC50:  2.65E+4nMAssay Description:Inhibition of human recombinant eNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355310(CHEMBL1835113)
Affinity DataIC50:  4.01E+4nMAssay Description:Inhibition of CYP2C19 using CEC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355310(CHEMBL1835113)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 using CEC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355310(CHEMBL1835113)
Affinity DataIC50:  7.27E+4nMAssay Description:Inhibition of CYP2C9 using MFC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355310(CHEMBL1835113)
Affinity DataIC50:  6.32E+4nMAssay Description:Inhibition of CYP2D6 using AMMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355310(CHEMBL1835113)
Affinity DataIC50:  7.48E+4nMAssay Description:Inhibition of CYP3A4 using BFC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355310(CHEMBL1835113)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 using BQ as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355310(CHEMBL1835113)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of human recombinant iNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed