BDBM50355469 CHEMBL1835744
SMILES Nc1nc(Nc2ccccc2Cl)nn1-c1ccc(cn1)C#N
InChI Key InChIKey=QYZYODZZZGIMSS-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50355469
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [33P]ATP from human recombinant FLT3 domain after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Inhibition of IRAK4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+3nMAssay Description:Inhibition of Aurora A by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of JAK2 by spectrophotometryMore data for this Ligand-Target Pair