BDBM50355634 CHEMBL1910967

SMILES Nc1cccc(c1)C#Cc1ccc(C(O)=O)c(SCc2ccc(Cl)c(Cl)c2)c1

InChI Key InChIKey=VOKUNEUMASWNEC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355634   

TargetReceptor-type tyrosine-protein phosphatase gamma(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50355634(CHEMBL1910967)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of RPTPgamma expressed in Escherichia coli BL21 (DE3) assessed as reduction in dephosphorylation of Z'-Lyte phospho-Tyr 1 peptide preincub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50355634(CHEMBL1910967)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of CD45 expressed in Escherichia coli BL21 (DE3) assessed as reduction in dephosphorylation of Z'-Lyte phospho-Tyr 1 peptide preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50355634(CHEMBL1910967)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) assessed as reduction in dephosphorylation of Z'-Lyte phospho-Tyr 1 peptide preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed