BDBM50355734 CHEMBL1911155
SMILES CCS(=O)(=O)c1ccc(cc1)-c1ccc2[C@H](c3ccccc3Oc2n1)C(C)(C)C(=O)Nc1nncs1
InChI Key InChIKey=QDRMJTWDTXUBPM-QFIPXVFZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50355734
Affinity DataKi: 4nMAssay Description:Displacement of GS-red from glucocorticoid receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 22.8nMAssay Description:Transrepression activity at glucocorticoid receptor alpha in IL-1beta-stimulated human A549 cells assessed as inhibition of NFkappaB-dependent E-sele...More data for this Ligand-Target Pair
Affinity DataEC50: 196nMAssay Description:Transactivation activity at GR-alpha in human NP1 Hela cells assessed as inhibition of GAL4-DBD after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 28.6nMAssay Description:Transrepression activity at glucocorticoid receptor alpha in phorbol myristate acetate-stimulated human A549 cells assessed as inhibition of AP1 resp...More data for this Ligand-Target Pair
Affinity DataEC50: 206nMAssay Description:Transactivation activity at GR-alpha in human NP1 Hela cells assessed as induction of GAL4-DBD after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Transactivation activity at glucocorticoid receptor alpha human 13D3/Huh7 cells assessed as induction of TAT activity after 4 hrs by spectrophotometr...More data for this Ligand-Target Pair