BDBM50355743 CHEMBL1911153
SMILES CC(C)([C@@H]1c2ccccc2Oc2nc(ccc12)-c1ccc(O)cc1)C(=O)Nc1nncs1
InChI Key InChIKey=ZAJFFJDEVBHMIF-HXUWFJFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50355743
Affinity DataKi: 5.70nMAssay Description:Displacement of GS-red from glucocorticoid receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 108nMAssay Description:Transrepression activity at glucocorticoid receptor alpha in IL-1beta-stimulated human A549 cells assessed as inhibition of NFkappaB-dependent E-sele...More data for this Ligand-Target Pair
Affinity DataEC50: 90.8nMAssay Description:Transrepression activity at glucocorticoid receptor alpha in phorbol myristate acetate-stimulated human A549 cells assessed as inhibition of AP1 resp...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Transactivation activity at GR-alpha in human NP1 Hela cells assessed as induction of GAL4-DBD after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 201nMAssay Description:Transactivation activity at GR-alpha in human NP1 Hela cells assessed as inhibition of GAL4-DBD after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair