BDBM50356492 CHEMBL1912002

SMILES Cn1cnc(CN(CCCNCc2ccc3OCOc3c2)c2nc(ns2)-n2ccnc2)c1

InChI Key InChIKey=TUAKJJMDPJADIG-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50356492   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50356492(CHEMBL1912002)
Affinity DataEC50:  71nMAssay Description:Inhibition of human iNOS expressed in human HEK293 cells assessed as nitrite accumulation after 18 hrs by 2,3-diaminonapthalene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50356492(CHEMBL1912002)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human eNOS expressed in HEK293 cells assessed as inhibition A23187-induced nitric oxide production incubated for 24 hrs measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50356492(CHEMBL1912002)
Affinity DataEC50:  1.80E+4nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin-induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed