BDBM50356634 CHEMBL1914702
SMILES ONC(=O)CCCCCCNC(=O)c1cc(on1)-c1ccc(NC(=O)c2cc(CN=[N+]=[N-])cc(c2)N=[N+]=[N-])cc1
InChI Key InChIKey=CRPIWCWIMAOUCX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50356634
Affinity DataKi: 23nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 651nMAssay Description:Inhibition of human recombinant HDAC8 using fluor de Lys as substrate preincubated for 5 mins followed by substrate addition measured after 25 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 932nMAssay Description:Inhibition of human recombinant HDAC5 using fluorophore-conjugated substrate Boc-L-Lys(Ac)-AMC after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant HDAC6 using fluorophore-conjugated substrate Boc-L-Lys(Ac)-AMC after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of human recombinant HDAC7 using fluorophore-conjugated substrate Boc-L-Lys(Ac)-AMC after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant HDAC9 using fluorophore-conjugated substrate Boc-L-Lys(Ac)-AMC after 60 minsMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 776nMAssay Description:Inhibition of human recombinant HDAC10 using fluorophore-conjugated substrate Boc-L-Lys(Ac)-AMC after 60 minsMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:Inhibition of human recombinant HDAC11 using fluorophore-conjugated substrate Boc-L-Lys(Ac)-AMC after 60 minsMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 1.08E+5nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant HDAC3/NCoR2 using fluorophore-conjugated substrate Boc-L-Lys(Ac)-AMCMore data for this Ligand-Target Pair
Affinity DataIC50: 651nMAssay Description:Inhibition of human recombinant HDAC8 using Fluor de Lys as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant HDAC1 using fluorophore-conjugated substrate Boc-L-Lys(Ac)-AMC after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Inhibition of human recombinant HDAC2 using fluorophore-conjugated substrate Boc-L-Lys(Ac)-AMC after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 432nMAssay Description:Inhibition of human recombinant HDAC4 using fluorophore-conjugated substrate Boc-L-Lys(Ac)-AMC after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 9.33E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair