BDBM50357348 CHEMBL1916906

SMILES CNc1cc2c(cc1F)nc(Nc1ccccc1C)c1cncn21

InChI Key InChIKey=IBPATAZNVCJILR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357348   

TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357348(CHEMBL1916906)
Affinity DataIC50:  19nMAssay Description:Inhibition of LYN-A expressed in Sf9 cells after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357348(CHEMBL1916906)
Affinity DataIC50:  40nMAssay Description:Inhibition of human full-length BTK expressed in Sf9 cells using FAM-Srctide peptide as substrate after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed