BDBM50357587 CHEMBL1915438
SMILES Clc1ccccc1Nc1nc2c(cccc2c2cnccc12)-c1nnc[nH]1
InChI Key InChIKey=WNOHFJIMKSDPHP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50357587
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 30 uM [ATP]More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of PIM2 by millipore assay in the presence of 15 uM [ATP]More data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Inhibition of PIM3 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 155 uM [ATP]More data for this Ligand-Target Pair
Affinity DataIC50: 104nMAssay Description:Inhibition of FLT3 using EAIYAAPFAKKK as substrate by radiometric assay in the presence of 200 uM [ATP]More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PIM1 in presence of ATP by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 4.80E+3nMAssay Description:Inhibition of FLT3 phosphorylation at Tyr591 in human MV-4-11 cells assessed as phospho-FLT3 level after 4 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PIM1 using KKRNRTLTV as substrate by millipore assay in the presence of 90 uM [ATP]More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair