BDBM50359166 CHEMBL1922986

SMILES Cn1cc(\C=C2/C(=O)NN=C2c2nccs2)c2c(OCc3cccc(F)c3F)cccc12

InChI Key InChIKey=OJCSMNPIXLENHY-GDNBJRDFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50359166   

TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50359166(CHEMBL1922986)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of GST-tagged intracellular domain of IR by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50359166(CHEMBL1922986)
Affinity DataIC50:  90nMAssay Description:Inhibition of nucleophosmin-fused ALK autophosphorylation in human Karpas299 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50359166(CHEMBL1922986)
Affinity DataIC50:  14nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed