BDBM50359519 CHEMBL1927157

SMILES Clc1ccccc1-n1[nH]c2cc(=O)n3CCCN(Cc4ccccn4)Cc3c2c1=O

InChI Key InChIKey=XCEHGPJYDIOHTC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50359519   

TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359519(CHEMBL1927157)
Affinity DataKi:  67nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359519(CHEMBL1927157)
Affinity DataKi:  113nMAssay Description:Antagonist activity at human NOX1 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 5(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359519(CHEMBL1927157)
Affinity DataKi:  543nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50359519(CHEMBL1927157)
Affinity DataKi:  1.14E+3nMAssay Description:Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed