BDBM50360295 CHEMBL1933282::US9150577, 76

SMILES O=C(Nc1nc2ccccc2n1-c1ccccc1)c1ccc2cc3C(=O)NCCCn3c2c1

InChI Key InChIKey=YARFNYLGLQVPEB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50360295   

TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50360295(CHEMBL1933282 | US9150577, 76)
Affinity DataIC50:  61nMpH: 7.5Assay Description:Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50360295(CHEMBL1933282 | US9150577, 76)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50360295(CHEMBL1933282 | US9150577, 76)
Affinity DataIC50:  61nMAssay Description:Inhibition of human RSK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed