BDBM50360304 CHEMBL516093::US9149492, Beauveriolide I

SMILES CCCC[C@H](C)[C@@H]1CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C)C(=O)N[C@H](CC(C)C)C(=O)O1

InChI Key InChIKey=ZKSLFHXTWGEITF-JIORRVSTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50360304   

TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dartmouth College

US Patent
LigandPNGBDBM50360304(CHEMBL516093 | US9149492, Beauveriolide I)
Affinity DataIC50:  600nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dartmouth College

US Patent
LigandPNGBDBM50360304(CHEMBL516093 | US9149492, Beauveriolide I)
Affinity DataIC50:  780nMAssay Description:Inhibition of ACAT1- mediated cholesteryl ester synthesis in macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
Dartmouth College

US Patent
LigandPNGBDBM50360304(CHEMBL516093 | US9149492, Beauveriolide I)
Affinity DataIC50:  2.00E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In DepthDetails US Patent