BDBM50360609 CHEMBL1933551

SMILES C[C@@H]1CCC(CN1)N1CC[C@@]2(C1)CN(C(=O)c1cc3ccccc3[nH]1)c1ccccc21

InChI Key InChIKey=XXRJWFOMOOANJW-MKBNCEHSSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50360609   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50:  2.34E+3nMAssay Description:Inhibition of MerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PKCzetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Cdk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Gsk3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IKKiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MAPKAP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Pak4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Pim-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50:  6.61E+3nMAssay Description:Inhibition of CK1deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of HGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of AxlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50:  246nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed