BDBM50361146 CHEMBL1933775
SMILES Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1-c1ccccc1
InChI Key InChIKey=YNQAUNMBAVKOIN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50361146
TargetNatural resistance-associated macrophage protein 2(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 520nMAssay Description:Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching methodMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of N-terminal His6-tagged human KDM4E (1 to 337 residues) catalytic domain measured formaldehyde dehydrogenase (FDH)-coupled fluorescence ...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 preincubated for 10 mins ...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 preincubated for 10 mins ...More data for this Ligand-Target Pair