BDBM50361249 CHEMBL1934891

SMILES Cc1ccc(NC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)NO)cc1

InChI Key InChIKey=IFSUDRKRFIOLEE-UHFFFAOYSA-N

Data  2 KI  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50361249   

TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361249(CHEMBL1934891)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361249(CHEMBL1934891)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361249(CHEMBL1934891)
Affinity DataKd: >1.00E+5nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-L-Lys(acetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361249(CHEMBL1934891)
Affinity DataKd:  3.40E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361249(CHEMBL1934891)
Affinity DataKd:  1.40E+4nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-L-Lys(acetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase-like amidohydrolase(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
University Of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361249(CHEMBL1934891)
Affinity DataKd:  270nMAssay Description:Inhibition of Bordetella FB188 HDAH using Boc-L-Lys(acetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University Of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361249(CHEMBL1934891)
Affinity DataKd:  5.20E+4nMAssay Description:Inhibition of recombinant human HDAC7 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed