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BDBM50362267 CHEMBL1939578

SMILES: CCC(CC)c1nc(C)c2nc(c(C)cn12)-c1ccc(OC)cc1C

InChI Key: InChIKey=KQAKZZOVMJLFRH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362267   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50362267
PNG
(CHEMBL1939578)
Show SMILES CCC(CC)c1nc(C)c2nc(c(C)cn12)-c1ccc(OC)cc1C
Show InChI InChI=1S/C21H27N3O/c1-7-16(8-2)21-22-15(5)20-23-19(14(4)12-24(20)21)18-10-9-17(25-6)11-13(18)3/h9-12,16H,7-8H2,1-6H3
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 311n/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counter


Bioorg Med Chem 20: 1122-38 (2012)


Article DOI: 10.1016/j.bmc.2011.11.015
BindingDB Entry DOI: 10.7270/Q2B27VQT
More data for this
Ligand-Target Pair