BDBM50362783 CHEMBL1940178

SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC1)C1CC1

InChI Key InChIKey=ZRQHFJCEWQABGC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50362783   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362783(CHEMBL1940178)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MET using Bio-HER2tide as substrate by TR-FRET assay in presence of 50 uM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362783(CHEMBL1940178)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of ALK using Bio-Gastrintide as substrate by TR-FRET assay in presence of 30 uM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362783(CHEMBL1940178)
Affinity DataIC50:  4.21E+3nMAssay Description:Inhibition of KDR using Bio-Gastrintide as substrate by TR-FRET assay in presence of 50 uM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362783(CHEMBL1940178)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of KIT using Bio-HER2tide as substrate by TR-FRET assay in presence of 50 uM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed