BDBM50363258 CHEMBL1944712

SMILES Fc1ccc2c(CN(c3cccc(Cl)c3)c3ccccn3)cc(=O)[nH]c2c1F

InChI Key InChIKey=JLGHPGGDKLOKAZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50363258   

TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Afraxis

Curated by ChEMBL
LigandPNGBDBM50363258(CHEMBL1944712)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human eNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Afraxis

Curated by ChEMBL
LigandPNGBDBM50363258(CHEMBL1944712)
Affinity DataIC50:  31nMAssay Description:Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Afraxis

Curated by ChEMBL
LigandPNGBDBM50363258(CHEMBL1944712)
Affinity DataIC50:  170nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed