BDBM50363447 CHEMBL1946325

SMILES COc1ccc(Nc2ncc3nc(Nc4ccccc4F)n(C4CCCC4)c3n2)cc1

InChI Key InChIKey=IMFVPVKPQOQCBY-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50363447   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363447(CHEMBL1946325)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of full length Hexa-His-tagged JNK1 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363447(CHEMBL1946325)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of p38alpha using MBP and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363447(CHEMBL1946325)
Affinity DataIC50:  210nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50363447(CHEMBL1946325)
Affinity DataIC50:  120nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed