BDBM50363826 CHEMBL1947129

SMILES CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(=O)NCc1ccccc1OC

InChI Key InChIKey=NKVLENIRXUJTOR-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50363826   

TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Beijing Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50363826(CHEMBL1947129)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [125I]Sar1 Ile8-Ang 2 from angiotensin 2 AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
Beijing Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50363826(CHEMBL1947129)
Affinity DataKd:  6.92nMAssay Description:Antagonist activity at angiotensin 2 AT1 receptor in Japanese White rabbits thoracic aorta assessed as inhibition of KCl-indcuced contraction after 6...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Beijing Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50363826(CHEMBL1947129)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of [125I]Sar1 Ile8-Ang 2 from angiotensin 2 AT2 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed