BDBM50364335 CHEMBL1950089
SMILES Cc1n[nH]c2nc3c(C)cc(Cl)cc3c(C(O)c3ncco3)c12
InChI Key InChIKey=MTYKIQDYUJLUDE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50364335
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of human recombinant PDE10A assessed as hydrolysis of cAMP to AMP using [3H]cAMP substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Reversible inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Time dependent inhibition of CYP3A4More data for this Ligand-Target Pair