BDBM50364559 CHEMBL1951032

SMILES COc1c(Nc2ccc(nc2C)S(C)(=O)=O)ncnc1OC1CCN(CC1)C(=O)OC(C)C

InChI Key InChIKey=WPDCHTSXOPUOII-UHFFFAOYSA-N

Data  4 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50364559   

TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364559(CHEMBL1951032)
Affinity DataEC50:  421nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364559(CHEMBL1951032)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364559(CHEMBL1951032)
Affinity DataEC50:  46nMAssay Description:Inhibition of human GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364559(CHEMBL1951032)
Affinity DataEC50:  46nMAssay Description:Agonist activity at human GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364559(CHEMBL1951032)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364559(CHEMBL1951032)
Affinity DataEC50:  46nMAssay Description:Agonist activity at human GPR119 receptor assessed as cAMP production by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364559(CHEMBL1951032)
Affinity DataEC50:  421nMAssay Description:Agonist activity at rat GPR119 receptor assessed as cAMP production by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364559(CHEMBL1951032)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364559(CHEMBL1951032)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364559(CHEMBL1951032)
Affinity DataEC50:  421nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed