BDBM50364672 CHEMBL1951461::US8785634, 3

SMILES FC(F)(F)Oc1ccc(CN2CCC3(CC2)OC(c2cccnc32)c2cc(Cl)cc(Cl)c2)cc1

InChI Key InChIKey=LKCGVBONYVRCLD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50364672   

TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364672(CHEMBL1951461 | US8785634, 3)
Affinity DataIC50:  5.20nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364672(CHEMBL1951461 | US8785634, 3)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364672(CHEMBL1951461 | US8785634, 3)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed