BDBM50365790 CHEMBL1956569
InChI string: InChI=1S/C23H25N7O/c1-28(2)21-15-17(7-8-24-21)20-16-26-22(23-25-9-10-30(20)23)27-18-3-5-19(6-4-18)29-11-13-31-14-12-29/h3-10,15-16H,11-14H2,1-2H3,(H,26,27)
SMILES: CN(C)c1cc(ccn1)-c1cnc(Nc2ccc(cc2)N2CCOCC2)c2nccn12
InChI Key: InChIKey=FHVPVBVCPGYZIE-UHFFFAOYSA-N
Data: 1 IC50
Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MAP kinase-activated protein kinase 5 (Homo sapiens (human)) | BDBM50365790![]() (CHEMBL1956569) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents AffyNet ![]() | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Galapagos NV Curated by ChEMBL | Assay Description Inhibition of MAPKAPK5 | Bioorg Med Chem Lett 22: 2266-70 (2012) | |||||||||||
More data for this Ligand-Target Pair |