BDBM50365798 CHEMBL1956685

SMILES NC(=O)c1cc(co1)-c1cnc(Nc2ccc(cc2)N2CCOCC2)c2nccn12

InChI Key InChIKey=JRHQKCWEMQJDGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365798   

TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50365798(CHEMBL1956685)
Affinity DataIC50:  702nMAssay Description:Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50365798(CHEMBL1956685)
Affinity DataIC50:  88nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed