BDBM50366204 CHEMBL1957602
SMILES ONC(=O)[C@@H]1CSCN1S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1
InChI Key InChIKey=UCAJNLLYTGJPBY-HNNXBMFYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50366204
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
TargetStromelysin-1(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of MMP3 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MMP1 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair