BDBM50366800 OLOMOUCINE II

SMILES CC[C@H](CO)Nc1nc(NCc2ccccc2O)c2ncn(C(C)C)c2n1

InChI Key InChIKey=NDUVSANREQEDRE-CQSZACIVSA-N

Data  3 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50366800   

LigandPNGBDBM50366800(OLOMOUCINE II)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366800(OLOMOUCINE II)
Affinity DataEC50:  8.00E+4nMAssay Description:Agonist activity at N-type Cav2.2 channel expressed in tsA201 cell assessed as calcium current by whole-cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50366800(OLOMOUCINE II)
Affinity DataIC50:  270nMAssay Description:Inhibition of CDK5/P35 (unknown origin) using histone H1 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50366800(OLOMOUCINE II)
Affinity DataIC50:  815nMAssay Description:Inhibition of CDK9/CyclinT1 (unknown origin) using (YSPTSPS)2KK as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed