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BDBM50367009 CHEMBL603548

InChI string: InChI=1S/C17H21N6O7P/c18-14-11-15(21-8-20-14)23(17(22-11)19-6-9-4-2-1-3-5-9)16-13(25)12(24)10(30-16)7-29-31(26,27)28/h1-5,8,10,12-13,16,24-25H,6-7H2,(H,19,22)(H2,18,20,21)(H2,26,27,28)/t10-,12-,13-,16?/m1/s1

SMILES: Nc1ncnc2n(C3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)c(NCc3ccccc3)nc12

InChI Key: InChIKey=HSLKBHZNNBHDSE-AARXTDBFSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50367009   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine-5'-monophosphate dehydrogenase


(Escherichia coli (strain K12))
BDBM50367009
PNG
(CHEMBL603548)
Show SMILES Nc1ncnc2n(C3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)c(NCc3ccccc3)nc12
Show InChI InChI=1S/C17H21N6O7P/c18-14-11-15(21-8-20-14)23(17(22-11)19-6-9-4-2-1-3-5-9)16-13(25)12(24)10(30-16)7-29-31(26,27)28/h1-5,8,10,12-13,16,24-25H,6-7H2,(H,19,22)(H2,18,20,21)(H2,26,27,28)/t10-,12-,13-,16?/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
2.75E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of inosine monophosphate dehydrogenase in Escherichia coli


J Med Chem 24: 1155-61 (1982)

More data for this
Ligand-Target Pair