BDBM50367654 CHEMBL1237336
SMILES Fc1ccc(cc1)[C@H]1C[C@H](N2CCNCC2)c2ccccc12
InChI Key InChIKey=IEXNAGAJXPUXLE-MOPGFXCFSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50367654
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of [3H]5-HT transporter uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:In vitro inhibition of [3H]dopamine uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of [3H]spiperone binding to 5-hydroxytryptamine 2 receptor from rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:In vitro inhibition of [3H]norepinephrine uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck
Curated by ChEMBL
H. Lundbeck
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of [3H]prazosin binding to alpha-1 adrenergic receptor from rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat striatal membranesMore data for this Ligand-Target Pair