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BDBM50367666 CHEMBL1237324

SMILES: CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3ccc(F)cc23)c2ccc(F)cc2)C1=O

InChI Key: InChIKey=SWWJOJRZBIXCNX-UHFFFAOYSA-N

Data: 3 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50367666   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50367666
PNG
(CHEMBL1237324)
Show SMILES CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3ccc(F)cc23)c2ccc(F)cc2)C1=O
Show InChI InChI=1S/C27H34F2N4O/c1-19(2)33-16-15-32(27(33)34)14-11-30-9-12-31(13-10-30)26-18-24(20-3-5-21(28)6-4-20)23-8-7-22(29)17-25(23)26/h3-8,17,19,24,26H,9-16,18H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 35n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat striatal membranes


J Med Chem 31: 2247-56 (1989)


Article DOI: 10.1021/jm00120a003
BindingDB Entry DOI: 10.7270/Q2JQ11K7
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50367666
PNG
(CHEMBL1237324)
Show SMILES CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3ccc(F)cc23)c2ccc(F)cc2)C1=O
Show InChI InChI=1S/C27H34F2N4O/c1-19(2)33-16-15-32(27(33)34)14-11-30-9-12-31(13-10-30)26-18-24(20-3-5-21(28)6-4-20)23-8-7-22(29)17-25(23)26/h3-8,17,19,24,26H,9-16,18H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.80n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiperone binding to 5-hydroxytryptamine 2 receptor from rat cortical membranes


J Med Chem 31: 2247-56 (1989)


Article DOI: 10.1021/jm00120a003
BindingDB Entry DOI: 10.7270/Q2JQ11K7
More data for this
Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))
BDBM50367666
PNG
(CHEMBL1237324)
Show SMILES CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3ccc(F)cc23)c2ccc(F)cc2)C1=O
Show InChI InChI=1S/C27H34F2N4O/c1-19(2)33-16-15-32(27(33)34)14-11-30-9-12-31(13-10-30)26-18-24(20-3-5-21(28)6-4-20)23-8-7-22(29)17-25(23)26/h3-8,17,19,24,26H,9-16,18H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 28n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of [3H]prazosin binding to alpha-1 adrenergic receptor from rat cortical membranes


J Med Chem 31: 2247-56 (1989)


Article DOI: 10.1021/jm00120a003
BindingDB Entry DOI: 10.7270/Q2JQ11K7
More data for this
Ligand-Target Pair